MOTS-C Peptide

MOTS-c stands for Mitochondrial Open Reading Frame of the 12S rRNA Type-C. It is a naturally occurring 16-amino-acid peptide encoded directly by the mitochondrial DNA rather than the cell's nucleus.

What Does It Do?

Often called an "exercise mimetic", MOTS-c plays a crucial role in regulating cellular energy and metabolism:

• Metabolism: It helps the body process glucose and fats more efficiently by activating the AMPK pathway.

• Cellular Health: Released under stress or during exercise, it acts as a stress-adaptor.

• Anti-aging: Levels naturally decline with age, and research in animals suggests it may help combat age-related physical decline and insulin resistance.

Status and Usage

While studied for potential anti-aging and metabolic therapies, it is currently not approved for human use by the FDA and is entirely prohibited in sports.